University of Karachi
|Assistant Professor (BPS-19)
Karachi, Sindh, Pakistan
Summary
Leads comprehensive teaching, research, and academic service initiatives within the Department of Pharmacognosy, focusing on mechanistic validation of natural products and fostering next-generation pharmaceutical scientists.
Highlights
Led an independent and coherent research program in mechanistic Pharmacognosy for over two decades, integrating Natural Product Chemistry, Experimental Pharmacology, and molecular disease mechanisms to validate medicinal plants for chronic diseases.
Pioneered and applied reproducible in vitro crystal growth inhibition models (brushite, calcium oxalate systems), providing mechanistic validation for traditional antiurolithiatic plant therapies and addressing a significant public health burden in Pakistan.
Conducted extensive mechanistic investigations into plant-derived compounds, elucidating molecular pathways (NF-κB, MAPK, PI3K/Akt) for therapeutic effects in chronic inflammatory, metabolic, and neurodegenerative diseases.
Expanded research into cancer pharmacology, identifying plant- and marine-derived bioactives as modulators of cancer cell survival (apoptosis, ferroptosis, cell cycle arrest) across hematological and solid tumors through national and international collaborations.
Authored over 125 peer-reviewed publications in HEC-recognized and internationally indexed journals (h-index 24, cumulative impact factor >100), alongside scholarly books and chapters, significantly advancing Pharmacognosy knowledge.
Mentored and successfully supervised multiple M.Phil. research scholars, fostering next-generation scientific talent in experimental design, data interpretation, scientific writing, and ethical research conduct.
Contributed significantly to academic governance through active membership in Boards of Studies, Boards of Faculty, Quality Enhancement Cell, and research committees, enhancing institutional academic standards.
Served as an invited reviewer for over 40 international journals (e.g., Elsevier, Springer, MDPI, Frontiers), ensuring research quality assurance and scholarly integrity at national and international levels.